Diabetes patients - Micardis HCT may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. No overall differences in effectiveness and safety were observed in these patients compared to younger patients and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. buy cheap ciprofloxacin store europe
In placebo-controlled trials involving 1041 patients treated with various doses of Micardis 20 to 160 mg monotherapy for up to 12 weeks, the overall incidence of adverse events was similar to that in patients treated with placebo. Lifestyle changes that may help this medication work better include stress reduction programs, exercise, and dietary changes. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make.
The medicine can only be obtained with a prescription. How is Micardis used? When telmisartan is used in fixed combination with amlodipine or hydrochlorothiazide, advise patients of important precautionary information about the concomitant agent. Do not crush, chew, or break a telmisartan tablet. Swallow it whole. There are no trials of Micardis demonstrating reductions in cardiovascular risk in patients with hypertension, but at least one pharmacologically similar drug has demonstrated such benefits. Warner KK, Visconti JA, Tschampel MM. Angiotensin II receptor blockers in patients with ACE inhibitor-induced angioedema. Ann Pharmacother.
Myers MG, Tobe SW. A Canadian perspective on the Eighth Joint National Committee JNC 8 hypertension guidelines. J Clin Hypertens Greenwich. Biphasic; terminal half-life is approximately 24 hours. Wright JT, Fine LJ, Lackland DT et al. Evidence supporting a systolic blood pressure goal of less than 150 mm Hg in patients aged 60 years or older: the minority view. Ann Intern Med.
Always tell your doctor if you are using a dietary supplement or if you are thinking about combining a dietary supplement with your conventional medical treatment. It may not be safe to forgo your conventional medical treatment and rely only on a dietary supplement. Sica DA. Angiotensin receptor blockers and the risk of malignancy: a note of caution. Drug Saf. Micardis HCT may interfere with certain lab tests, including parathyroid function tests. Be sure your doctor and lab personnel know you are taking Micardis HCT. It is driving me crazy! Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Dosage adjustments may be necessary. 2 See Hepatic Impairment under Dosage and Administration. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. Martineau P, Goulet J. New competition in the realm of renin-angiotensin axis inhibition; the angiotensin II receptor antagonists in congestive heart failure. Ann Pharmacother. Hypotension may be more common in patients receiving Micardis to prevent cardiovascular problems. For the full list of all side effects reported with Micardis, see the package leaflet. Deterioration of renal function may occur. 1 2 See Renal Effects under Cautions. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Read the "How to Open the Blister" at the end of this leaflet before you use Micardis. Talk with your doctor if you do not understand the instructions. Dosage of Micardis is individualized. The usual starting dose is 40 mg once a day. Micardis may interact with water pills or digoxin. Tell your doctor all medications you are taking. Micardis is not recommended for use during pregnancy due to the risk for harm to a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding. You should not use this medication if you are unable to urinate or if you are allergic to hydrochlorothiazide, telmisartan, or sulfa drugs. Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may increase your blood pressure.
Three studies examined the use of CoQ10 along with conventional treatment for cancer. Tell your doctor or dentist that you take Micardis HCT before you receive any medical or dental care, emergency care, or surgery. Diarrhea; dizziness; nausea; tiredness. American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. Lithium: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists including Micardis. Therefore, monitor serum lithium levels during concomitant use. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. DOQI Clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease 2002. From National Kidney Foundation website. Go AS, Bauman MA, Coleman King SM et al. An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention. Hypertension. Support for use to reduce the risk of cardiovascular events was obtained in a pair of studies. Izzo JL, Levy D, Black HR. Importance of systolic blood pressure in older Americans. Hypertension. It is not known whether hydrochlorothiazide and telmisartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medication. Use with caution. The effects may be increased because of slower removal of the medicine from the body. aprovel
BP reduction may be smaller in black patients than in patients of other races. 1 See Hypertension under Uses. Micardis can cause harm or death to an unborn baby. Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant. If you get pregnant while taking Micardis, tell your doctor right away. This product may affect your levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Volpe M, Morganti A. 2010 Position Paper of the Italian Society of Hypertension SIIA: Angiotensin Receptor Blockers and Risk of Cancer. High Blood Press Cardiovasc Prev. In rare cases, telmisartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine. Effect of losartan on renal and cardiovascular complications of patients with type 2 diabetes and nephropathy. Talk to your doctor or about lifestyle changes that might benefit you. The presence of other medical problems may affect the use of this medicine. kles.info cabergoline
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Although the event rates in ONTARGET were similar on telmisartan and ramipril, the results did not unequivocally rule out that Micardis may not preserve a meaningful fraction of the effect of ramipril in reducing cardiovascular events. However, the results of both ONTARGET and TRANSCEND do adequately support Micardis being more effective than placebo would be in this setting, particularly for the end point of time to cardiovascular death, myocardial infarction, or stroke. Manufacturers state fixed-combination preparation should not be used for initial antihypertensive therapy. Injury or death to your unborn baby. See "What is the most important information I should know about Micardis tablets? Use not recommended in those with severe hepatic impairment. Mazzolai L, Burnier M. Comparative safety and tolerability of angiotensin II receptor antagonists. Drug Safety. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. If you have any questions about Micardis HCT, please talk with your doctor, pharmacist, or other health care provider. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take up to 4 weeks before you get the full benefit of this drug. The antihypertensive effect of angiotensin II receptor antagonists, including telmisartan may be attenuated by NSAIDs including selective COX-2 inhibitors. The only serious adverse events at least 1% more common on telmisartan than placebo were intermittent claudication 7% vs 6% and skin ulcer 3% vs 2%. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Plasma protein binding is constant over the concentration range achieved with recommended doses. The volume of distribution for telmisartan is approximately 500 liters indicating additional tissue binding. What are the ingredients in Micardis tablets? Viberti G, Mogensen CE, Groop LC et al. Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. JAMA. American Heart Association Task Force on Practice Guidelines. Circulation. price of travatan cough syrup india
The following adverse reactions have been identified during post-approval use of Micardis. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate reliably their frequency or establish a causal relationship to drug exposure. Decisions to include these reactions in labeling are typically based on one or more of the following factors: 1 seriousness of the reaction, 2 frequency of reporting, or 3 strength of causal connection to Micardis. Of the total number of patients receiving Micardis in hypertension clinical studies, 551 19% were 65 to 74 years of age and 130 4% were 75 years or older. No overall differences in effectiveness and safety were observed in these patients compared to younger patients and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. Micardis is available as tablets for oral administration, containing 20 mg, 40 mg or 80 mg of telmisartan. The tablets contain the following inactive ingredients: sodium hydroxide, meglumine, povidone, sorbitol, and magnesium stearate. Micardis tablets are hygroscopic and require protection from moisture. Littlejohn T, Mroczek W, Marbury T et al. A prospective, randomized, open-label trial comparing telmisartan 80 mg with valsartan 80 mg in patients with mild to moderate hypertension using ambulatory blood pressure monitoring. Can J Cardiol. Stangier J, Su CPF, Schöndorfer G et al. Pharmacokinetics and safety of intravenous and oral telmisartan 20 mg and 120 mg in subjects with hepatic impairment compared with healthy volunteers. J Clin Pharmacol.
This information should not be used to decide whether or not to take Micardis HCT or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Micardis HCT. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Micardis HCT. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Micardis HCT. Have your blood pressure checked regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor. What should I discuss with my healthcare provider before taking Micardis HCT hydrochlorothiazide and telmisartan? Coenzymes help work to digest food and perform other body processes, and they help protect the and skeletal muscles. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. In patients with hepatic insufficiency, plasma telmisartan concentrations are increased and absolute bioavailability approaches 100%. Tell your doctor if your condition does not improve or if it worsens such as your blood pressure readings remain high or increase. purchase now online naproxen
It is not known if Micardis is safe and effective in children. Treatment of essential hypertension in adults. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of telmisartan. Lab tests, including kidney function, blood pressure, and blood electrolytes, may be performed while you use Micardis HCT. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. The population studied was 73% male, 74% Caucasian, 14% Asian, and 57% were 65 years of age or older. Baseline therapy included acetylsalicylic acid 76% lipid lowering agents 64% beta-blockers 57% calcium channel blockers 34% nitrates 29% and diuretics 28%. It may take 2 to 4 weeks before your symptoms improve. Keep using the medicine as directed and tell your doctor if your symptoms do not improve. BP meds. My Dr. said I have to over look the side effects. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Report prolonged or to your doctor. Be sure to drink enough fluids to prevent unless your doctor directs you otherwise. ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. Digoxin: When Micardis was co-administered with digoxin, median increases in digoxin peak plasma concentration 49% and in trough concentration 20% were observed. Therefore, monitor digoxin levels when initiating, adjusting, and discontinuing telmisartan for the purpose of keeping the digoxin level within the therapeutic range. Multiple sub-group analyses did not demonstrate any differences in the 4-component composite primary endpoint based on age, gender, or ethnicity for either ONTARGET or TRANSCEND trial. Plasma concentrations of telmisartan are generally 2 to 3 times higher in females than in males. In clinical trials, however, no significant increases in blood pressure response or in the incidence of orthostatic hypotension were found in women. No dosage adjustment is necessary. Only some of the studies of coenzyme Q10 showed that it helps heart failure symptoms. Telmisartan is a white to slightly yellowish solid. It is practically insoluble in water and in the pH range of 3 to 9, sparingly soluble in strong acid except insoluble in hydrochloric acid and soluble in strong base. Rare, serious allergic reactions may happen. pyridostigmine
Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure JNC V. Arch Intern Med. Do not keep outdated medicine or medicine no longer needed. Ponikowski P, Voors AA, Anker SD et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology ESCDeveloped with the special contribution of the Heart Failure Association HFA of the ESC. Boehringer Ingelheim. Micardis HCT telmisartan and hydrochlorothiazide tablets prescribing information. Micardis HCT may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away. No substantial differences in safety or efficacy relative to younger adults, but increased sensitivity cannot be ruled out. The dosage is based on your medical condition and response to treatment. Blockade of the renin-angiotensin system with ACE inhibitors, which inhibit the biosynthesis of angiotensin II from angiotensin I, is widely used in the treatment of hypertension. ACE inhibitors also inhibit the degradation of bradykinin, a reaction also catalyzed by ACE. Because telmisartan does not inhibit ACE kininase II it does not affect the response to bradykinin. Whether this difference has clinical relevance is not yet known. Telmisartan does not bind to or block other hormone receptors or ion channels known to be important in cardiovascular regulation. carbidopa
This medicine is available only with your doctor's prescription. Ask your health care provider any questions you may have about how to use Micardis HCT. Store Micardis HCT at 77 degrees F 25 degrees C. Brief storage at temperatures between 59 and 86 degrees F 15 and 30 degrees C is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Micardis HCT out of the reach of children and away from pets. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Micardis may affect the way other medicines work, and other medicines may affect how Micardis works. AHA guidelines for the evaluation and management of chronic heart failure in the adult. Rare cases of rhabdomyolysis have been reported in patients receiving angiotensin II receptor blockers, including Micardis. This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the dose at the same time each day.
Micardis or ramipril alone. Plasma concentration of angiotensin II and plasma renin activity PRA increased in a dose-dependent manner after single administration of telmisartan to healthy subjects and repeated administration to hypertensive patients. The once-daily administration of up to 80 mg telmisartan to healthy subjects did not influence plasma aldosterone concentrations. In multiple dose studies with hypertensive patients, there were no clinically significant changes in electrolytes serum potassium or sodium or in metabolic function including serum levels of cholesterol, triglycerides, HDL, LDL, glucose, or uric acid. Perk J, De Backer G, Gohlke H et al. European Guidelines on cardiovascular disease prevention in clinical practice version 2012. The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice constituted by representatives of nine societies and by invited experts. Kaplan NM. Choice of initial therapy for hypertension. JAMA. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Fagundes Neto U, Franco L, Tabacow K, Machado NL. Negative findings for use of coconut water as an oral rehydration solution in childhood diarrhea. Blocks the physiologic actions of angiotensin II, including vasoconstrictor and aldosterone-secreting effects. This list is not complete. Other drugs may interact with telmisartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. All medicines may cause side effects, but many people have no, or minor, side effects. Other than for vitamins and minerals, the long-term effects of most dietary supplements are not known. What is Cardiovascular Risk? Qaseem A, Hopkins RH, Sweet DE et al. Screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease: A clinical practice guideline from the American College of Physicians. Ann Intern Med. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. The way dietary supplements are manufactured may not be standardized. Because of this, how well they work or any side effects they cause may differ among brands or even within different lots of the same brand. The form of supplement that you buy in health food or grocery stores may not be the same as the form used in research. buy norethisterone dosage
Howes LG, Tran D. Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema? Coenzyme Q10 is a substance similar to a vitamin. It is found in every cell of the body. Your body makes CoQ10, and your cells use it to produce energy your body needs for cell growth and maintenance. When used in fixed combination with amlodipine or hydrochlorothiazide, consider the cautions, precautions, and contraindications associated with the concomitant agent. Micardis telmisartan is an II receptor used to treat . Micardis is sometimes given together with other blood pressure medications. There is also an AT 2 receptor found in many tissues, but AT 2 is not known to be associated with cardiovascular homeostasis. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Take this medication by mouth with or without food as directed by your doctor, usually once daily. For individual components of the primary composite endpoints, all events, regardless whether or not they were the first event, were considered. Therefore, they are more than the first events considered for the primary or secondary composite endpoint. Side effects with Micardis are not common. American Diabetes Association. Standards of medical care in diabetes--2014. Diabetes Care. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Food and Drug Administration. FDA drug safety communication: No increase in risk of cancer with certain blood pressure drugs-angiotensin receptor blockers ARBs. Rockville, MD; 2011 Jun 2. Available from FDA website. This medication passes into milk. Consult your doctor before -feeding. In the treatment of essential hypertension, Micardis was more effective than placebo at reducing diastolic blood pressure and had similar effects to the other medicines for hypertension. Upon initiation of antihypertensive treatment with telmisartan, blood pressure was reduced after the first dose, with a maximal reduction by about 4 weeks. With cessation of treatment with Micardis tablets, blood pressure gradually returned to baseline values over a period of several days to one week. During long term studies without placebo control the effect of telmisartan appeared to be maintained for up to at least one year. lumigan shop 24 hour
If adequate BP response not achieved with a single antihypertensive agent, add a second drug with demonstrated benefit; if goal BP still not achieved with optimal dosages of 2 antihypertensive agents, add a third drug. 501 May maximize dosage of the first drug before adding a second drug, or add a second drug before maximizing dosage of the initial drug. FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Hydrochlorothiazide and telmisartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control. Micardis HCT may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Micardis HCT with caution. This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions. Parving HH, Lehnert H, Brochner-Mortensen J et al and the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med. Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You might have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Boehringer Ingelhein Pharmaceuticals, Inc. Twynsta telmisartan and amlodipine besylate tablets prescribing information. Ridgefield, CT; 2014 Dec. The incidence of adverse events was not dose-related and did not correlate with gender, age, or race of patients. You may take this medicine with or without food. Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs. Importance of instructing patients not to remove tablets from the blister package until immediately before administration. If your symptoms do not improve or if they become worse, check with your doctor. How should I take Micardis HCT hydrochlorothiazide and telmisartan? Some people take it to help reduce the effects certain medicines can have on the heart, muscles, and other organs. If oliguria or hypotension occurs, direct attention toward support of blood pressure and renal perfusion. zocor
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Management of hypertension alone or in combination with other classes of antihypertensive agents; 1 2 3 17 19 132 500 may be used in fixed combination with amlodipine or hydrochlorothiazide when such combined therapy is indicated. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Micardis as soon as possible. These adverse outcomes are usually associated with use of these drugs in the second and third trimester of pregnancy. Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agents. Appropriate management of maternal hypertension during pregnancy is important to optimize outcomes for both mother and fetus.
Side Effects List Micardis HCT side effects by likelihood and severity. In rare cases, hydrochlorothiazide and telmisartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed. How should I take telmisartan?
Other Drugs: Co-administration of telmisartan did not result in a clinically significant interaction with acetaminophen, amlodipine, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen. Telmisartan is not metabolized by the cytochrome P450 system and had no effects in vitro on cytochrome P450 enzymes, except for some inhibition of CYP2C19. Telmisartan is not expected to interact with drugs that inhibit cytochrome P450 enzymes; it is also not expected to interact with drugs metabolized by cytochrome P450 enzymes, except for possible inhibition of the metabolism of drugs metabolized by CYP2C19.